Dexmedetomidine (Precedex) is not indicated for infusions lasting longer than 24 hours.
Dexmedetomidine (Precedex) should be administered using a controlled infusion device.
Dosage Information: See Table 7.

Dosage Adjustment: Due to possible pharmacodynamic interactions a reduction in dosage of Dexmedetomidine (Precedex) or other concomitant anesthetics, sedatives, hypnotics or opioids may be required when co-administered. (See Interactions.)
Dosage reductions may need to be considered for adult patients with hepatic impairment, and geriatric patients (see Precautions and Pharmacology: Pharmacokinetics under Actions).