Dexmedetomidine in 0.9% Sodium Chloride (Precedex Premix) Solution for Intravenous Infusion is a sterile, nonpyrogenic ready to use solution suitable for intravenous infusion.
Dexmedetomidine hydrochloride is a central alpha2-adrenergic agonist. Dexmedetomidine is the S-enantiomer of medetomidine. Dexmedetomidine hydrochloride chemical name is 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride, (S). Dexmedetomidine has a molecular weight of 236.7 and the empirical formula is C13H16N2·HCl.
Dexmedetomidine is a white or almost white powder that is freely soluble in water and has a pKa of 7.1. Its partition coefficient in-octanol: water at pH 7.4 is 2.89.
Dexmedetomidine in 0.9% sodium chloride (Precedex Premix) Solution for Intravenous Infusion is ready to be used. It is supplied as a clear, colorless, isotonic solution with a pH between 4.5 to 8.0. The solution is preservative-free and contains no additives or chemical stabilizers.
Dexmedetomidine in 0.9% sodium chloride (Precedex Premix) Solution for Intravenous Infusion: Each mL contains 4.72 mcg of dexmedetomidine hydrochloride (equivalent to 4 mcg or 0.004 mg of dexmedetomidine) and 9 mg sodium chloride in water.
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