Gastrointestinal discomfort, diarrhea or gas constipation, nausea vomiting, drowsiness and dizziness have been observed. Signs of hemolytic anemia should be watched in cases when the drug is taken for a prolonged period of time, as in all inhibitors of prostaglandin synthesis. Mefenamic acid can affect platelet function. In large doses, the drug may induced grand mal convulsions hence, it is suggested to avoid this in epileptics.