Use in Pregnancy: Anaphylaxis is a fairly uncommon event in pregnancy that can have serious implications for both mother and fetus. Several central nervous system damage in the preterm fetus and death in infancy have been attributed to maternal hypotensive anaphylaxis whereas at term the fetus has been regarded as protected. Severe fatal complication after intravenous application of ampicillin to a woman at term has been reported. This case demonstrates that the fetus near term may not be protected against severe damage caused by anaphylaxis. Therefore drugs with the potential to produce anaphylactic reactions should be given with caution in pregnancies at term. Intensive fetal monitoring in anaphylactic reaction is necessary to allow rapid delivery of the infant.
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