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Should not be used when the following medical problem exists: History of previous allergic reactions (anaphylaxis) to penicillins, penicillin derivatives, penicillamine, or cephalosporins.
Risk-benefit should be considered when the following medical problems exist: History of gastrointestinal disease especially, ulcerative colitis, regional enteritis, or antibiotic-associated colitis.
Renal function impairment.
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