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Hypersensitivity to hydrocortisone or to any component of the product.
Bacterial infections unless specific anti-infective is given, systemic fungal and viral infections (due to immunosuppressing action, infection can be exacerbated).
Patients with herpes simplex, herpes zoster and chicken pox.
Patients with articular cavity infection or peritonitis/tenosynovitis (infection may be exacerbated by immunosuppression effect).
Patients with articular cavity instability.
Administration of live or live attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids.
Intramuscular administration of corticosteroid is contraindicated for idiopathic thrombocytopenic purpura.
Intrathecal administration is contraindicated. Reports of severe medical events have been associated with this route of administration.
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