Pediamox Special Precautions

A thorough inquiry about the patient's previous hypersensitivity history should be made. Amoxicillin, like other penicillins, cephalosporins and other drugs, may cause serious hypersensitivity reactions and should be used with caution in any patient who has demonstrated some allergy to any drug. There is clinical and laboratory evidence of partial cross-allergenicity among penicillins and other beta-lactam antibiotics including cephalosporins and cephamycins.
Use in Renal Failure: The dose of amoxicillin may have to be reduced due to prolonged plasma half-life.
Use in Pregnancy & Lactation: Amoxicillin has been administered to pregnant women without evidence of adverse effects to the fetus. The use of amoxicillin is currently included in the US Center for Disease Control and Prevention (CDC) recommendations for the treatment of chlamydial infections during pregnancy and for the treatment of cutaneous anthrax or for post-exposure prophylaxis after exposure to Bacillus anthracis spores.
Use with caution in breastfeeding mothers because amoxicillin is distributed into milk and may lead to sensitization of infants.
Use in Elderly: No special precautions have to be taken when prescribing for the elderly.