Patryl Dosage/Direction for Use

Tablet: Adults: Amoebic Dysentery: Initially 2 g as single dose for 2 days, then 500 mg 3 times a day for 5-10 days.
Hepatic and Other Extraintestinal Amoebiasis: 500-800 mg thrice daily or 2 g as a single dose for 2 days.
Giardiasis: 2 g daily as a single dose for 3 successive days.
Children 7-10 years: ½ of the adult dose.
Suspension: ≥10 years: 1-2 tsp (15-30 mL); 5-10 years: 2 tsp (15-30 mL); 2-5 years: 1 tsp (5 mL). Daily dose is administered every 8 hrs, 1 hr before meal.
Injection: Adults and Children >12 Years: 100 mL by IV 8 hourly. The injection should be infused IV at the rate of 5 mL/min, but may be administered alone or concurrently but separately, with other bacteriological appropriate antibacterial agents in parenteral dosage forms. Oral medication with 400 mg 3 times daily should be substituted as soon as this becomes feasible. Treatment for 7 days should be satisfactorily for most patients but depending upon clinical and bacteriological assessments, the physician might decide to prolong treatment eg, for the eradication of infection from sites which cannot be drained or are liable to endogenous recontamination by anaerobic pathogens from the gut, oropharynx or genital tract.
100 mL by IV infusion immediately before, during or after an operation, followed by the same dose 8 hourly until oral medication can be given to complete a 7-day course. In infants and other patients maintained on IV fluids metronidazole injection may be diluted with appropriate volumes of normal saline, dextro-saline, dextrose 5% or potassium chloride injections. Or prescribed by the physician.
Children <12 Years: As for adults, but the single IV dose is based on 1.5 mL/kg body weight (metronidazole 7.5 mg/kg body mass) and the oral dose of 7 mg/kg body mass. Or as prescribed by the physician.