Ofev Description

Nintedanib esilate (Ofev) capsules, 100 mg are peach-coloured, opaque, oblong, soft gelatin capsules, imprinted in black on one side with the Boehringer Ingelheim company symbol and with "100". The capsule contains a bright yellow viscous suspension.
Nintedanib esilate (Ofev) capsules, 150 mg are brown-coloured, opaque, oblong, soft gelatin capsules, imprinted in black on one side with the Boehringer Ingelheim company symbol and with "150". The capsule contains a bright yellow viscous suspension.
Each capsule contains 100 mg or 150 mg of nintedanib (= free base) corresponding to 120.4 mg or 180.6 mg 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl] amino]phenyl] amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-, ethanesulfonate (1:1) (= nintedanib esilate).
Excipients/Inactive Ingredients: Capsule fill: Medium chain triglycerides, hard fat, soya lecithin (E322).
Capsule shell: Gelatin, glycerol 85%, titanium dioxide (E171), iron oxide red (E172), iron oxide yellow (E172), black ink (Opacode).
Black ink: Shellac glaze, iron oxide black (E172), propylene glycol (E1520).