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Each mL of Nubain ampule also contains sodium chloride 2 mg, sodium citrate 9.41 mg and anhydrous citric acid 12.62 mg; pH is adjusted with hydrochloric acid.
Nalbuphine HCl is (-)-17-(cyclobutylmethyl)-4, 5α-epoxymorphinan-3, 6α, 14-triol hydrochloride. It is a synthetic agonist-antagonist analgesic of the phenanthrene series which is chemically related to both the widely used narcotic antagonist, naloxone and the potent analgesic, oxymorphone.
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