Nocid Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Pantoprazole

Indications/Uses

Conditions where inhibition of gastric acid secretion may be beneficial, including aspiration syndromes, dyspepsia, GERD, PUD & Zollinger-Ellison syndrome.

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Dosage/Direction for Use

GERD 20-40 mg once daily for 4 wk, increased to 8 wk if necessary & up to 16 wk for healing erosive esophagitis. Maintenance: Continued w/ 20-40 mg once daily. Recurrent symptoms 20 mg daily alternatively. PUD 40 mg once daily; 2-4 wk for duodenal ulceration & 4-8 wk for benign gastric ulceration. Eradication of H. pylori Combined w/ 2 antibacterial in 1-wk regimen: 40 mg bid combined w/ clarithromycin 500 mg bid & either amoxicillin 1 g bid or metronidazole 400 mg bid. Patient requiring prophylaxis for NSAID-associated ulceration 20 mg daily. Zollinger-Ellison syndrome Initially 80 mg daily, adjusted as required.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity.

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Special Precautions

Possibility of malignancy should be considered. Hepatic impairment.

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Adverse Reactions

Headache, diarrhea, skin rashes; pruritus, dizziness, fatigue, constipation, nausea & vomiting, flatulence, abdominal pain, arthralgia, myalgia, urticaria, dry mouth.

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Drug Interactions

May alter metabolism of drugs metabolized by CYP2C19 isoenzymes. May prolong elimination of diazepam, phenytoin, tolbutamide & warfarin. May reduce absorption of drugs whose absorption is dependent on acid gastric pH eg, ketoconazole & possibly itraconazole. Increased plasma conc w/ voriconazole.

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Storage

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Description

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Action

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MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

Presentation/Packing

Form

Nocid cap 40 mg

Packing/Price

100's

Nocid

omeprazole

pantoprazole

Manufacturer:

Nutramedica

Distributor:

Nutramedica