Mycozole cap Systemic candidiasis 400 mg on day 1, followed by 200 mg daily for 28 days.
Cryptococcal meningitis 400 mg for acute & 200 mg for relapse on day 1, followed by 200 mg daily for 10-12 wk after CSF culture becomes -ve.
Superficial mucosal candidiasis 50 mg daily, if necessary, 100 mg may be given. Treatment usually continues for 7-14 days in oropharyngeal candidiasis (except in severely immunocompromised patients), 14 days in atrophic oral candidiasis associated w/ dentures & mucosal candidal infections including esophagitis for 14-30 days.
Vag candidiasis 150 mg as single dose.
Dermatophytosis, pityriasis versicolor & Candida infections 50 mg daily for up to 6 wk.
Immunocompromised patient at risk of fungal infections Prophylactic dose: 50-400 mg daily.
Childn >4 wk Superficial infection 3 mg/kg daily. Loading dose: 6 mg/kg may be used on the 1st day if necessary.
Systemic infections 6-12 mg/kg daily.
Prophylaxis in immunocompromised childn 3-12 mg/kg daily.
Infants 2-4 wk Administer every 48 hr,
>2 wk Administer every 72 hr.
Mycozole IV soln for infusion 2 mg/mL at a rate of 5-10 mL/min (300-600 mL/hr). Max: 100 mL/hr.
Childn >4 wk Systemic infections 6-12 mg/kg daily.
Prophylaxis in immunocompromised childn 3-12 mg/kg daily.
Infant <2 wk All doses should be given once every 72 hr;
2 & 4 wk Doses should be given every 48 hr. Max of 400 mg daily in childn or 12 mg/kg in infant.
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