Metrinox IV Indications/Uses

Systemic metronidazole is indicated for the treatment of: Vaginitis due to Trichomonas vaginalis (protozoal) infection in both symptomatic patients as well as their asymptomatic sexual contacts; and due to bacterial Gardnerella or Mycoplasma hominis infection in symptomatic patients.
Pelvic inflammatory disease in conjunction with other antibiotics such as ofloxacin, levofloxacin, or ceftriaxone.
Protozoal infections due to Entamoeba histolytica (Amoebic dysentery or Hepatic abscesses), and Giardia lamblia (Giardiasis) should be treated alone or in conjunction with iodoquinol or diloxanide furoate.
Anaerobic bacterial infections such as Bacteroides fragilis spp, Fusobacterium spp, Clostridium spp, Peptostreptococcus spp, Prevotella spp, or any other anaerobes in intraabdominal abscess, peritonitis, empyema, pneumonia, aspiration pneumonia, lung abscess, diabetic foot ulcer, meningitis and brain abscess, bone and joint infections, septicemia, endometritis, tubo-ovarian abscess, or endocarditis.
Pseudomembranous colitis due to Clostridium difficile.
Helicobacter pylori eradication therapy, as part of a multi-drug regimen in peptic ulcer disease.
Prophylaxis for those undergoing potentially contaminated colorectal surgery and may be combined with neomycin.
Acute gingivitis and other dental infections (TGA approved, non-Food and Drug Administration (FDA) approved).
Crohn's disease with colonic or perianal involvement (non-FDA approved).