Metrinox IV Drug Interactions

Co-administration of metronidazole and ethanol (alcohol) results, rarely, in a disulfiram-like reaction (nausea, vomiting, flushing, tachycardia).
Consumption of alcohol should be avoided by patients during systemic metronidazole therapy and for at least 24 hours after completion of treatment. However, the occurrence of this reaction in the clinical setting has recently been questioned by some authors.
This drug should not be used with the following medications because very serious interactions may occur: amprenavir solution taken by mouth, disulfiram, lopinavir/ritonavir solution taken by mouth.
If the patient is currently using any of these medications listed previously, tell the doctor or pharmacist before starting metronidazole.
Before using this medication, tell the doctor or pharmacist of all prescription and nonprescription/herbal products the patient may use, especially of: "blood thinners" (e.g., warfarin), busulfan, cimetidine, corticosteroids (e.g., methylprednisolone, prednisone), fluorouracil, lithium, drugs for seizures (e.g., phenobarbital, phenytoin), live bacterial vaccines.
This medication may interfere with certain laboratory tests (including liver function tests, blood triglyceride levels), possibly causing false test results. Make sure laboratory personnel and all the doctors know the patient use this drug.