Medixon Special Precautions

While being treated with corticosteroid, patients should not be vaccinized or immunized to smallpox, especially with high doses to prevent the possibility of neurologic complications.
If corticosteroid is applied in patients with latent tuberculosis or tuberculin reactivity, patients should be observed carefully as reactivation of the disease may occur.
Corticosteroids effects may increase in patients with hypothyroidism or cirrhosis.
Use with caution in patients with ocular herpes simplex because of possible corneal perforation.
Medixon can suppress clinical symptoms of an infectious disease.
Long-term treatment may decrease the body's stamina to infectious disease.
Use in pregnancy & lactation: Methylprednisolone may cause fetal damage when administered to pregnant women. Corticosteroids can diffuse into breast milk and placenta and may cause side effects and suppress growth in nursing infants.
Use in children: The administration of glucocorticoids in children should be avoided because it may cause retardation. If therapy is necessary, infant growth should be closely monitored. Alternate-day therapy given as a single dose in the morning may minimize growth suppression and should be instituted if growth is minimized. High doses of glucocorticoids in children may cause acute pancreatitis followed by pancreatic destruction.
Use in the elderly: Hypertension may occur during adrenocorticoid therapy. Geriatric patients, especially postmenopausal women, may also be more likely to develop glucocorticoid-induced osteoporosis.