Should not be given to patients with peptic ulcerations and should be used with caution, if at all, in patients with history of such disorders. To reduce the risk of gastrointestinal effects, NSAIDs may be taken with or after food or milk.
NSAIDs should be used with caution in patients with infections, since symptoms such as fever and inflammation may be masked, and should also be used with caution in patients with asthma or allergic disorders.
Other general precautions to be observed include administration to patients with haemorrhagic disorders, hypertension, and impaired renal, hepatic, or cardiac function. Patients undergoing therapy with some NSAIDs may need to be monitored for the development of blood, kidney, liver or eye disorders. NSAIDs should be used with caution in the elderly and may need to be given in reduced doses.
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