Karvidol Dosage/Direction for Use

In hypertension carvedilol is given in an initial dose of 12.5 mg once daily by mouth, increased after two days to 25 mg once daily. Alternatively, an initial dose of 6.25 mg is given twice daily, increased after one to two weeks to 12.5 mg once daily. The dose may be increased further, if necessary, at intervals of at least two weeks, to 50 mg once daily or in divided doses. A dose of 12.5 mg once daily may be adequate for elderly patients.
In angina pectoris an initial dose of 12.5 mg is given twice daily by mouth, increased after two days to 25 mg twice daily.
In heart failure 3.125 mg is given by mouth twice daily for two weeks. The dose may be then be increased, if tolerated, to 6.25 mg twice daily. The dosage should be increased as tolerated at intervals of at least two weeks to a maximum recommended dose of 25 mg twice daily for patients weighing less than 85 kg or 50 mg twice daily for patients weighing more than 85 kg.