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Use in Pregnancy: The use of drugs that act directly on the renin-angiotensin system during the second and third trimesters of pregnancy has been associated with fetal and neonatal injury, including hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, and death. Because of the possibility that irbesartan may have a similar effect on the fetus, it should not be used during pregnancy.
Use in Lactation: Irbesartan should be avoided in nursing mothers.
