Intramol Dosage/Direction for Use

Adults and Children over 12 years: Recommended therapy is one drop of Timolol ophthalmic solution in the affected eye(s) twice a day.
Elderly: Dosage need not be modified for the elderly as there has been wide experience with the use of Timolol ophthalmic solution in elderly patients.
Children below the age of 12 years: This product is currently not recommended for use.
It is recommended that therapy is initiated using Timolol 0.25% ophthalmic solution. If the clinical response is not adequate, the dosage may be increased to one drop of Timolol 0.5% ophthalmic solution in each affected eye twice daily. Intraocular pressure should be reassessed approximately four weeks after starting treatment because response to Timolol ophthalmic solution may take a few weeks to stabilize. Provided that intraocular pressure is maintained at satisfactory levels, many patients can be placed on once daily therapy.
If necessary, concomitant treatment with miotics, epinephrine and/or carbonic anhydrase inhibitors can be instituted. In order to prevent the active substance from being washed out when additional ophthalmic medication is used, an interval of at least 10 minutes between each application is recommended. The use of two topical beta-adrenergic agents is not recommended.
Transfer from topical beta-blocking agents: Discontinue use after a full day of therapy and start treatment with Timolol ophthalmic solution the next day, with one drop in each affected eye twice daily.
Transfer from a single anti-glaucoma agent other than a topical beta-blocking agent: Continue the agent and add one drop of Timolol ophthalmic solution in each affected eye twice daily. On the following day, discontinue the previous agent completely, and continue with Timolol ophthalmic solution.