Glevate Adverse Reactions

The most frequent adverse reactions reported for Clobetasol Cream have been local and have included burning sensation and stinging sensation. Less frequent adverse reactions were itching, skin atrophy, cracking and fissuring of the skin.
The following local adverse reactions are reported infrequently when topical corticosteroids are used as recommended. These reactions, listed in an approximately decreasing order of occurrence are burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.
Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestation of Cushing's Syndrome, hyperglycaemia and glycosuria in some patients. In rare instances, treatment (or withdrawal of treatment) of psoriasis with corticosteroids is thought to have provoked the pustular form of the disease.