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Forcad

Forcad Drug Interactions

simvastatin

Manufacturer:

Lloyd

Distributor:

Corbridge
Full Prescribing Info
Drug Interactions
There is an increased risk of myopathy if certain drugs are given concurrently with statins. Concomitant administration of drug that inhibit the cytochrome P450 isoenzyme CYP3A4, such as ciclosporin, itraconazole, ketoconazole, erythromycin, clarithromycin, HIV-protease inhibitors, and nefazodone, might produce high plasma levels of Simvastatin, thus increasing the risk of myopathy. Drugs that alone can cause myopathy, such as fibric acid derivatives or nicotinic acid, can increase the risk of this reaction when given with Simvastatin.
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