The usual adult dose by mouth is 0.5 to 1 g every 4 to 6 hours up to a maximum of 4 g daily. Usual doses in children are: under 3 months, 10 mg per kg body weight (reduce to 5 mg per kg if jaundiced); 3 months to 1 year, 60 mg to 120 mg; 1 to 5 years, 120 to 250 mg; 6 to 12 years, 250 to 500 mg. These doses may be given every 4 hours to 6 hours when necessary up to maximum of 4 doses in 24 hours. For post-immunisation pyrexia, a dose of 60 mg has been recommended for children 2 to 3 months of age. A second dose may be given after four to six hours; if the pyrexia persists after the dose, the parent should seek medical device. Rectal doses for adults and children over 12 years of age are 0.5 to 1 g. Rectal doses in younger children are: 1 to 5 years, 125 to 250 mg; 6 to 12 years, 250 to 500 mg. Doses may be administered up to 4 times daily.
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