Fexitas Adverse Reactions

The following adverse reactions will be considered listed: Blood and lymphatic system disorders: Eosinophilia, Hypereosinophilia, Agranulocytosis, Leucopenia, Neutropenia, Granulocytopenia, Hemolytic anemia, Thrombocytopenia, Thrombocytosis.
Gastrointestinal Disorders: Abdominal pain, Diarrhea*, Dyspepsia, Nausea, Vomiting, Flatulence.
Hepatobiliary Disorders: Jaundice.
Infections and Infestations: Pseudomembranous colitis, Vaginitis.
Investigations: Aspartate aminotransferase increased, Alanine aminotransferase increased, Blood bilirubin increased, Blood urea increased, Blood creatinine increased.
Nervous system disorders: Dizziness, headache, cases convulsions have been reported with cephalosporins including cefixime (frequency not known)**.
Beta-lactams, including cefixime, predispose the patient to encephalopathy risk (which may include convulsions, confusion, impairment of consciousness, movement disorders), particularly in case of overdose or renal impairment (frequency not known)**.
Respiratory, thoracic and mediastinal disorders: Dyspnea.
Renal and urinary disorders: Acute renal failure with tubulointerstitial nephritis.
Immune System Disorders: Anaphylactic Reactions, Angio-edema, Serum sickness-like reaction.
Skin and subcutaneous tissue disorders: Drug rash with eosinophilia and systemic symptoms (DRESS), Erythema multiforme, Stevens-Johnson syndrome, Toxic epidermal necrolysis, Urticaria, Rash, Pruritus, Acute generalised exanthematous pustulosis (AGEP).
General Disorders and administrative site conditions: Drug fever, Arthralgia, Pyrexia, Face edema, Genital pruritus.
*Diarrhea has been more commonly associated with higher doses. Some cases of moderate to severe diarrhea have been reported; this has occasionally warranted cessation of therapy. Cefixime (Fexitas) should be dicontinued if marked diarrhea occurs.
**Cannot be estimated from available data.