The recommended course of etoposide Injection is 60-100 mg/m2, IV, daily for five consecutive days. As etoposide produces myelosuppression, courses may not be repeated more frequently than at 3 weeks intervals.
The dosage may vary according to the symptom.
Immediately before administration, the required dose of etoposide Injection must be diluted with 0.9% saline solution for injection to give a solution concentration of not more than 0.25 mg/mL of etoposide; it should then be given by intravenous infusion over a period of not less than 30 minutes. Care should be taken to avoid extravasation.
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