Eroxmit 500 Special Precautions

Special care is indicated in patients who have experienced an allergic reaction to penicillins or other beta-lactams.
As with other antibiotics, prolonged use of Cefuroxime (as axetil) may result in the overgrowth of other nonsusceptible organisms (eg, Candida, Enterococci, Clostridium difficile), which may require interruption of treatment.
Pseudomembranous colitis has been reported with the use of broad-spectrum antibiotics, therefore, it is important to consider its diagnosis in patients who develop serious diarrhea during or after antibiotic use.
The Jarisch-Herxheimer reaction has been seen following Cefuroxime (as axetil) treatment of Lyme disease. It results directly from the bactericidal activity of Cefuroxime (as axetil) on the causative organism of Lyme disease, the spirochaete Borrelia burgdorferi. Patients should be reassured that this is a common and usually self-limiting consequence of antibiotic treatment of Lyme disease.
With a sequential therapy regimen the timing of change to oral therapy is determined by severity of the infection, clinical status of the patient and susceptibility of the pathogens involved. If there is no clinical improvement within 72 hrs, then the parenteral course of treatment must be continued.
Effects on the Ability to Drive or Operate Machinery: As medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.