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Pregnancy: There are no adequate data from the use of Calcipotriol + Betamethasone (Dipsotrex B) in pregnant women. Studies in animals with glucocorticoids have shown reproductive toxicity, but a number of epidemiological studies have not revealed congenital anomalies among infants born to women treated with corticosteroid during pregnancy. The potential risk for humans is uncertain. Therefore, during pregnancy, Calcipotriol + Betamethasone (Dipsotrex B) should only be used when the potential benefit justifies the potential risk.
Lactation: Betamethasone passes into breast milk, but risk of an adverse effect on the infant seems unlikely with therapeutic doses. There are no data on the excretion of calcipotriol in breast milk.
Caution should be exercised when prescribing Calcipotriol + Betamethasone (Dipsotrex B) to women who breast-feed.
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