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Treatment of type 2 diabetes mellitus in adults, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycemic control.
Metformin may be used as monotherapy or in combination with other oral antidiabetic agents, or with insulin.
Intensive glucose control with metformin as first-line therapy after diet failure in overweight type 2 diabetic patients has been shown to reduce diabetes complications.
Impaired glucose tolerance (IGT) for patients in whom lifestyle interventions (diet and exercise) have failed.
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