Denigma Adverse Reactions

The following Adverse Drug Reactions mentioned as follows have been accumulated in clinical studies with memantine tablets and since its introduction in the market. Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Adverse reactions are ranked according to system organ class, using the following convention: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000), not known (cannot be estimated from the available data).
Infections and infestations: Uncommon: Fungal infections.
Immune system disorders: Common: Drug Hypersensitivity.
Psychiatric disorders: Common: Somnolence. Uncommon: Confusion, Hallucinations¹. Not known: Psychotic reactions².
Nervous system disorders: Common: Dizziness, Balance disorders. Uncommon: Gait abnormal. Very rare: Seizures.
Cardiac disorders: Uncommon: Cardiac failure.
Vascular disorders: Common: Hypertension. Uncommon: Venous thrombosis/thromboembolism.
Respiratory, thoracic and mediastinal disorders: Common: Dyspnoea.
Gastrointestinal disorders: Common: Constipation. Uncommon: Vomiting. Not known: Pancreatitis².
Hepatobiliary disorders: Common: Elevated liver functions test. Not known: Hepatitis.
General disorders and administration site conditions: Common: Headache. Uncommon: Fatigue.
¹ Hallucinations have mainly been observed in patients with severe Alzheimer's disease.
² Isolated cases reported in post-marketing experience.
Alzheimer's disease has been associated with depression, suicidal ideation and suicide. In post-marketing experience these reactions have been reported in patients treated with Memantine hydrochloride (Denigma).
Seek medical attention immediately at the first sign of any adverse drug reaction shall appear.