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Caution should be used when prescribing Clindamycin Phosphate to individuals with a history of gastrointestinal disease, especially colitis. Periodic liver and kidney function tests should be carried out during prolonged therapy. Such monitoring is also recommended in neonates and infants. Safety and appropriate dosage in infants less than one month old have not been established.
Prolonged administration of Clindamycin Phosphate, as with any anti-infective, may result in super-infection due to organisms resistant to clindamycin. Care should be observed in the use of Clindamycin Phosphate in atopic individuals.
