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Adult Inhalation anthrax: 500 mg (base) every 12 hour for 60 days.
Bone and joint infections: Mild to moderate 500 mg (base) every 12 hour for at least 4-6 week.
Severe or complicated infections: 750 mg (base) every 12 hour for at least 4-6 week.
Mild to moderate infectious diarrhea: 500 mg (base) every 12 hour for 5-7 days.
Endocervical and urethral gonorrhea: 250 mg (base) as single dose.
Intra-abdominal infections: 500 mg (base) every 12 hour for at least 7-14 days in combination with oral Metronidazole.
Lower respiratory tract, skin and soft tissue infections: Mild to moderate: 500 mg (base) every 12 hour for at least 7-14 days; severe or complicated: 750 mg (base) every 12 hour for 7-14 days.
Mild to moderate chronic prostatitis: 500 mg (base) every 12 hour for 28 days.
Mild to moderate sinusitis or typhoid fever: 500 mg (base) every 12 hour for 10 days.
Acute complicated urinary tract infection: 100 mg (base) every 12 hour for 3 days; mild to moderate: 250 mg (base) every 12 hour for 7-14 days; severe or complicated: 500 mg (base) every 12 hour for 7-14 days. Max: 1.5 g (base) daily.
Children up to 18 yr Given only when alternative therapy could not be used.
Inhalation anthrax: 15 mg/kg body weight dose (base). Max: 500 mg/dose, every 12 hour for 60 days.
Other infections: 10-15 mg (base)/kg body weight twice daily, up to 1.5 g/day.
Elderly: Adult dose.
