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Ciprofloxacin should be used with caution in patients with epilepsy or a history of CNS disorders. Should not be used in children, adolescents, pregnant women, or breastfeeding mothers or use only if the benefits outweigh the risk.
Healthcare professionals are advised to avoid prescribing fluoroquinolones to patients who have aortic aneurysm or at risk for an aortic aneurysm, such as patients with peripheral atherosclerotic vascular disease, hypertension, certain genetic conditions such as Marfan syndrome and Ehlers-Danlos syndrome, and elderly patients. The benefit of using fluoroquinolones to these patients should be assessed by the prescribers prior to initiation of therapy. It should be prescribed to these patients only when no other treatment options are available.
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