Adult 100-400 mg bid, given over 30-60 min. Childn 4-8 mg/kg bid. Exacerbation of cystic fibrosis associated w/P. aeruginosainfection 10 mg/kg bid up to max of 400 mg bid.
Avoid use in patients who have or at risk for aortic aneurysm eg, patients w/ peripheral atherosclerotic vascular disease, HTN, Marfan & Ehlers-Danlos syndrome. Patients w/ epilepsy or history of CNS disorders. Not to be used during pregnancy & lactation. Not generally recommended for other uses in childn & adolescents. Elderly.
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