Cholivex Dosage/Direction for Use

It is prescribed intravenously in the form of a bolus intravenous injection (during 5 minutes) or slow intravenous infusion (40-60 drops per minute). The intravenous way of administration is more preferable, than intramuscular. It is necessary to avoid repeated administration of the drug to the same place during intramuscular administration.
Acute period of ischemic stroke and traumatic brain damage: Recommended dose after recognition is 100 mg for every 12 hours. Treatment period is not less than 6 weeks. 3-7 days after starting of treatment, intramuscular administration (1-2 injections per day) or oral administration (if swallow ability is damaged).
Rehabilitation period of ischemic and hemorrhagic stroke, rehabilitation period of traumatic brain damage, cognitive abnormalities at degenerate and vascular diseases of brain: Recommended dose is 500-2000 mg daily. Dose and treatment period depends on severity of symptoms.
At long-term impairment of consciousness continuous application of a drug from the first stages of disease is possible.
Geriatrics: No need for dose adjustment after administration of Cholivex.
Paediatric: Safety and efficacy have not been evaluated for children and teenage age below 18 years.
Solution for I.M./I.V. injection is designed for single administration. After ampoule is opened, solution should be used immediately.
Cholivex is compatible with I.V. isotonic solution and dextrose solutions.
Method of administration: Cholivex is administered by intramuscular injection or slow intravenous injection.