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Carbonic anhydrase inhibitor.
Pharmacokinetics: Acetazolamide is fairly rapidly absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 2 hrs after administration by mouth. It has been estimated to have a plasma half-life of about 3-6 hrs. It is tightly bound to carbonic anhydrase and high concentrations are present in tissues containing this enzyme, particularly RBCs and the renal cortex; it is highly bound to plasma proteins. It is excreted unchanged in the urine.
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