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Chronic Simple Glaucoma: 250 mg-1 g/24 hrs in divided doses.
Secondary Glaucoma/Preoperative Treatment of Some Cases of Acute Congestive Glaucoma: 250 mg 4 hrly. In some acute cases, an initial dose of 500 mg then 125-250 mg 4 hrly.
Epilepsy: 8-30 mg/kg in divided doses. Max: 375-1000 mg daily.
Congestive Heart Failure: 250-375 mg once daily in the morning.
Drug-induced Edema: 250-375 mg once a day for 1-2 days, alternating with a day of rest.
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