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Renal Impairment: Use with caution; dosage reduction may be necessary.
Monitor renal and hematological status, especially during prolonged or high-dose therapy.
Interferes with the Jaffe method for measuring creatinine; may produce falsely high values.
Effects on Gastrointestinal Tract: Significant changes in anaerobic, facultative, and aerobic flora observed.
Use in Lactation: See Use in Pregnancy & Lactation section for further information.
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