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In hypertension, the usual dose by mouth is 250 mg, two or three times daily for 2 days; this is then adjusted by small increments or decrements not more frequently than every 2 days according to the response of the patient. The usual maintenance dosage is 0.5 to 2 g of Methyldopa daily. In the elderly an initial dose of 125 mg twice daily has been recommended; this dose may be increased gradually if necessary, but should not exceed 2 g daily.
Or as directed by the physician.
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