Azithromycin is used in the treatment of respiratory-tract infections (including otitis media), in skin and soft-tissue infections, and in uncomplicated genital infections. It may also be used for the prophylaxis, and as a component of regimens in the treatment of Mycobacterium avium complex (MAC) infections. It is used in some countries for the prophylaxis of endocarditis in at risk patients unable to take penicillin. It is also used in the management of trachoma and typhoid.