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Trifarotene (Aklief) is for once-daily cutaneous use only.
If the medication is applied excessively, no more rapid or better results will be obtained and marked redness, scaling, or skin discomfort may occur. In this event, discontinue use and wait until the skin has recovered.
In case of accidental ingestion, appropriate symptomatic measures should be taken.
Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of vitamin A.
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