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The use of colchicine is contraindicated in: Pregnancy and lactation; People who are hypersensitive to colchicines; Children under 2 years of age; Blood dyscrasias; Uric acid kidney stones; Patients with renal or hepatic impairment who are taking a P-glycoprotein (P-gp) inhibitor or a strong CYP34A4 inhibitor.
Colchicine should not be used in patients undergoing haemodialysis since it cannot be removed by dialysis or exchange transfusion.
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