Discontinue use if signs & symptoms of severe cutaneous adverse reactions; movement disorders eg, parkinsonian symptoms, restless leg syndrome, tremors, postural instability occur. Not a curative treatment for angina attacks or as initial treatment for unstable angina, MI, pre-hospital phase or during 1st days of hospitalisation. Falls related to postural instability or hypotension. Positive results in anti-doping tests. May affect ability to drive & use machines. Moderate renal impairment. Avoid use during pregnancy. Not to be used during lactation. Childn <18 yr. Elderly >75 yr.