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Hypersensitivity to naproxen.
Patients who have previously shown hypersensitivity reactions (e.g. nasal polyps, asthma, rhinitis, angioedema or urticaria) in response to aspirin or other NSAIDs. These reactions have the potential of being fatal.
Severe hepatic, renal, and cardiac failure.
During the last trimester of pregnancy.
Active or previous history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
Active or a history of upper gastrointestinal bleeding or perforation related to previous NSAIDs therapy.
Children under 2 years of age.
