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Symptoms: Dizziness, nausea, vomiting, syncope, euphoria, hallucinations, headache, vasodilation and hypotension. Muscular twitching, tremors, hyperactive reflexes, dilated pupils and convulsions followed by respiratory depression and coma; local reactions.
Treatment: If the drug has been ingested, empty stomach by aspiration and lavage. Intensive supportive therapy may be necessary to correct respiratory failure and shock. Use specific antagonist, naloxone hydrochloride - 400 μg IV repeated at intervals of 2-3 minutes if necessary. In children, a dose of 5-10 μg/kg body weight may be given. Nalorphine hydrobromide and levallorphan tartrate have also been used. The circulation should be maintained with infusions of Dextrose Injection and suitable electrolyte solutions. Small doses of suxamethonium have also been suggested to control convulsions.
