Irritable bowel syndrome
Adult: 1 cap (0.2 mL) tid; may increase to 2 caps (0.4 mL) tid as necessary. Doses may be given for up to 2-3 months.
Indications and Dosage
Oral
Irritable bowel syndrome Adult: 1 cap (0.2 mL) tid; may increase to 2 caps (0.4 mL) tid as necessary. Doses may be given for up to 2-3 months.
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Special Precautions
Patient with heartburn; blood from the bowel, feeling of sickness or vomiting, loss of appetite or weight, paleness or tiredness, severe constipation, fever, abnormal vaginal bleeding or discharge, difficulty or pain in passing urine, gallstones. Hepatic impairment. Pregnancy and lactation.
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Adverse Reactions
Gastrointestinal disorders: Burining sensation, anorectal discomfort, dyspepsia, gastroesophageal reflux, nausea, vomiting.
Immune system disorders: Hypersensitivity. |
Overdosage
Symptoms: Severe nausea, vomiting, abdominal pain, vertigo, ataxia, drowsiness, coma. Management: Symptomatic and supportive treatment. Perform gastric lavage to empty the stomach.
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Action
Description:
Mechanism of Action: ppermint oil is an aromatic carminative which has inhibitory effect on the gastrointestinal smooth muscle. It acts by interfering with the mobilisation of Ca ions. |
Storage
Store below 25°C. Protect from light.
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MIMS Class
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References
Brayfield A, Cadart C (eds). Peppermint Leaf. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 04/12/2024. Chiesi New Zealand Limited. Colpermin Modified Release Capsule data sheet December 2024. Medsafe. http://www.medsafe.govt.nz. Accessed 04/12/2024. Colpermin (Tillotts). MIMS Hong Kong. http://www.mims.com/hongkong. Accessed 04/12/2024. Colpermin IBS Relief Capsules (McNeil Products Limited). MHRA. https://products.mhra.gov.uk. Accessed 04/12/2024. Joint Formulary Committee. Peppermint Oil. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 04/12/2024. Mintec Capsules (Teofarma S.r.l.). MHRA. https://products.mhra.gov.uk. Accessed 04/12/2024. Peppermint. UpToDate Lexidrug, Natural Products Database. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 04/12/2024.
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