The treatment with OSTENIL/OSTENIL MINI/OSTENIL PLUS is not recommended in children, pregnant and lactating women or in inflammatory joint diseases such as rheumatoid arthritis or Bechterew disease. In case of joint effusion, the effusion should be reduced first. The national guidelines for intra-articular injections must be observed, this includes thorough disinfection of the injection site and other measures to avoid joint infections. OSTENIL/OSTENIL MINI/OSTENIL PLUS should be injected accurately into the joint cavity, if necessary, under imaging control. Avoid injections into blood vessels or surrounding tissues. Do not use if the pre-filled syringe or sterile pack are damaged. Any solution not used immediately after opening must be discarded. Otherwise, the sterility is no longer guaranteed, and this may be associated with a risk of infection. Do not resterilize as this may damage the product. No information on the impairment of any diagnostic investigations, such as magnetic resonance imaging, clinical condition assessments or therapeutic treatments by OSTENIL/OSTENIL MINI/OSTENIL PLUS have been notified yet.
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