Oroplus Mechanism of Action

Pharmacology: Lidocaine is a local anaesthetic of the amide type and used to block nerves from sending messages to the brain. It has a rapid onset of action and anaesthesia is obtained within a few minutes. It has an intermediate duration of action. Lidocaine is a useful surface anaesthetic, it may be rapidly and extensively absorbed through mucous membranes following topical application to stop pain and inflammation.
Triamcinolone Acetonide is a corticosteroid with mainly glucocorticoid activity in anti-inflammatory to reduce redness and swelling of damaged tissues.
Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gram-positive and gram-negative bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extra microbial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.
Lidocaine is readily absorbed through damaged skin and from mucous membranes. Lidocaine is largely metabolized in the liver and about 90% is dealkylated to form monoethylglycinexylidine and glycinexylidine. Further metabolism occurs and metabolites are excreted in the urine with less than 10% of unchanged Lidocaine.
Corticosteroids are readily absorbed from the gastrointestinal tract.
Triamcinolone is reported to have a half-life in plasma of about 2 to over 5 hours. It is bound to plasma albumin to a much smaller extent than hydrocortisone.
Chlorhexidine is poorly absorbed from gastrointestinal tract and skin.