Discontinue use at 1st appearance of severe skin reactions eg, skin rash, mucosal lesions or any other sign of hypersensitivity; acute intolerance reactions eg, abdominal cramps & pain, fever, severe headache & rash occur. History of adverse drug reactions to sulphasalazine-containing prep. Patients w/ pulmonary disease eg, asthma; pre-existing skin conditions eg, atopic dermatitis & eczema. Determine blood tests (eg, differential blood count, liver function parameters & serum creatinine) prior to & during treatment. Ensure adequate fluid intake during treatment. Not to be used in renal impairment. Hepatic impairment. Pregnancy & lactation. Childn & adolescents.
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