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Local anaesthetics react with certain metals and cause the release of their respective ions which, if injected, may cause severe local irritation.
Adequate precautions should be taken to avoid prolonged contact between MARCAIN solutions and metal surfaces such as metal bowls, cannulae and syringes with metal parts.
Solutions showing discolouration and unused portions of solutions from ampoules should be discarded.
Polyamps should not be re-autoclaved. Surface sterilisation using pure, undiluted isopropyl alcohol (91%) or 70% ethanol maybe carried out if desired. Soaking of any MARCAIN presentation is not recommended.
