Amoxicillin and Clavulanic acid are combined in this medicine.
Amoxicillin + Clavulanic acid is an antibiotic. It is used to treat certain bacterial infections of the ears, nose, sinuses, lungs, bladder, skin, bones and joints.
This medicine may also be used to treat other conditions as decided by your doctor.
Take Amoxicillin + Clavulanic acid exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Ask your doctor or pharmacist whether you should take this medicine with or without food. Different preparations of this medicine may be taken differently.
Try to take it at the same time each day.
Amoxicillin + Clavulanic acid is available as a conventional or extended-release tablet and as a powder for oral suspension.
If you are taking the extended-release type of tablet (usually labeled as “ER” or “XR”), swallow it whole. Do not divide, chew or crush the tablet.
If you are taking the powder for oral suspension, tap or invert the bottle to loosen the dry powder and add the specified volume of water to reconstitute the suspension. Shake the bottle well before you take the medicine to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure your dose.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your infection.
Take Amoxicillin + Clavulanic acid at regular intervals. Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not be properly controlled.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Do not take Amoxicillin + Clavulanic acid if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or similar antibiotics such as penicillins (e.g. ampicillin) or cephalosporins (e.g. cefaclor, cefuroxime).
Alert your doctor if you have the following conditions:
- history of liver disease due to previous use of this medicine
- viral infection known as infectious mononucleosis
as Amoxicillin + Clavulanic acid may not be suitable for you.
Do not take the extended-release type of tablet if you have severe kidney disease or are undergoing dialysis (a procedure that helps individuals with kidney failure to filter toxic substances from the blood).
Inform your doctor if you have the following conditions:
- unable to pass urine regularly
- atopy (an inherited condition associated with heightened immune response to common allergens which may lead to allergic diseases including asthma)
- liver disease
- kidney disease or undergoing dialysis
Let your doctor know if you are pregnant or breastfeeding.
Be sure to check with your doctor or pharmacist before giving Amoxicillin + Clavulanic acid to a child. Children may be more sensitive to the side effects.
Do not switch between different preparations unless advised by your doctor.
If you are going to have certain laboratory tests (e.g. urine glucose tests), inform your doctor that you are taking this medicine.
Why is it important to keep my appointments with the doctor?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Routine tests (e.g. liver and kidney function, complete blood count) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
- Regular monitoring for signs of infection and allergic reactions may also be needed.
Amoxicillin + Clavulanic acid may cause any of the following side effects: headache, nausea, vomiting, diarrhoea, indigestion, itching, and thrush in the mouth, skin folds or vagina.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swollen eyes, face or mouth
- severe diarrhoea or diarrhoea with severe stomach cramps or bloody stools
- fits or seizures
- yellowing of the skin or eyes, abdominal pain, dark coloured urine, unusual tiredness, swelling in the legs and ankles
- rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for gout (high uric acid level in the blood) e.g. probenecid, allopurinol
- blood-thinning medicines e.g. warfarin, acenocoumarol
- mycophenolate mofetil (medicine used in organ transplants or certain immune disorders)
- methotrexate (medicine for cancer)
- birth control pills
This list does not include all medicines that may interact with Amoxicillin + Clavulanic acid.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in a cool, dry place away from the reach of children. Protect from moisture.
Refrigerate the oral suspension (between 2-8°C) once you have mixed the powder with water. Do not freeze it otherwise, it will become less effective. Throw away any unused portion based on the specific product recommendations.
Medicines must not be used past the expiry date
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