Hypersensitivity to tetracycline. Monotherapy in patients w/ complicated intra-abdominal infections secondary to clinically apparent intestinal perforation. Pseudomembranous colitis in patients w/ diarrhea. Carefully monitor patient during therapy to prevent superinfections. May impair ability to drive or operate machinery. Monitor patient w/ severe hepatic impairment. Pregnancy & lactation. Childn <18 yr.